ancillary-nucleotide-change-type

This value set includes only the types associated with nucleotide allele instances.

Scope and Usage

ancillaryNucleotideChangeType allows the use of an ancillary type which can be used to clarify and add depth to the primary type observed. This type also allows a single annotation using a term not included in the primary list.

ancillaryNucleotideChangeType:

Currently constraint to be a child of sequence_alteration within the Sequence Ontology. Accurate annotation of ancillary-nucleotide-change-type will not contain terms found in primary-nucleotide-change-type.

Examples:

ancillaryNucleotideChangeType: (cardinality of 0..*)

  • This attribute allows for a couple of possibilities.
    1. First to allow additional detail in describing the location of the feature related to the variant. 2. Second, it allows the uses of terms that may better describe the feature of intrest, not offered in the primary list.

The first case:

Type Display Name Code
primaryNucleotideChangeType deletion SO:0000159
ancillaryNucleotideChangeType inversion SO:1000036
Type Display Name Code
primaryNucleotideChangeType substitution SO:1000002
ancillaryNucleotideChangeType MNV SO:0002007

This method offers two levels of annotated detail. The primaryNucleotideChangeType term enables higher-level grouping, and the ancillaryNucleotideChangeType offers additional specifics on the nature of the variant.

The second case:

Type Display Name Code
ancillaryNucleotideChangeType deficient_intrachromosomal_transposition SO:0000062

Exclusions and Limitations

Additional terms can be submitted for review via the sequence ontology request a term